Conducting good, ethical global health research is now more important than ever. Increased global mobility and connectivity mean that in today’s world there is no such thing as ‘local health’. As a collection, these stories offer a flexible resource for training across a variety of contexts, such as medical research organizations, universities, collaborative sites, and NGOs. 

12th November 2017 • comment

Sarah Drew shares her research diary about conducting ethnographic fieldwork in Malawi as part of a Clubfoot study.

16th March 2017 • comment

This is a great video of a talk given at the Oxford Martin School by Professor Kevin Marsh.

10th March 2017 • comment

Become a Cochrane citizen scientist. Anyone can join their collaborative volunteer effort.

23rd December 2016 • comment

This excellent series of videos from Yale University provide an overview of qualitative research by Dr. Leslie Curry leads us through six modules covering essential topics in qualitative research, including what is qualitative research and how to use the most common methods, in-depth interviews and focus groups. These videos are intended to enhance participants' capacity to conceptualize, design, and conduct qualitative research in the health sciences. 

16th December 2016 • comment

10 Best resources on… intersectionality with an emphasis on low- and middle-income countries

by Elizabeth Larson, Asha George, Rosemary Morgan, Tonia Peteat

This article, published in Oxfordjournals.org, discusses the issue of intersectionality in health inequities, defniing the issueand directing the reader to helpful resources on the topic.   

15th December 2016 • comment
28th September 2016 • comment

Please see this Sky News interview where we were asked by Sky News to comment on the announcement about this bold vision to tackle all diseases.

26th September 2016 • comment

This framework describes key components of capacity development, indicators for their success and ways to verify capacity development.

22nd March 2016 • comment

Global Health Glossary

by The Editors

This glossary provides definitions of some common terms encountered in clinical research.

23rd February 2016 • comment

Authors conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the basis of these approaches, to propose guidance for RCT authors. Most identified approaches invite trial authors to report the extent of MPD and the underlying reasons. Fewer approaches focus on reporting missingness patterns, methods for handling MPD and implications of MPD on results. 

4th January 2016 • comment

Looking for a job in global health? A 4 part series that takes a look at what you need to do to get your career in global health off to a good start.

15th December 2015 • comment
1st December 2015 • comment

Dr Iveta Seimer, Deputy Director of the UK EQUATOR Centre, discusses research waste, reproducibility, and how to use reporting guidelines to make an impact. Poor reporting seriously affects the integrity of health research literature and critically limits the use and impact of published studies.

27th November 2015 • comment

New INTERGROWTH-21st Postnatal Growth Standards charts for individual measurements of length, weight, head circumference, as well as a combined standards chart for length, weight and head circumference are now available for download here.

9th November 2015 • comment
22nd September 2015 • comment

Field trials of interventions against disease in low and middle income countries (LMICs) may be complex and expensive undertakings. This 3rd edition of the Field Trials Toolbox has been compiled by over 30 contributors with extensive direct experience in the design, conduct, and analysis of field trials in LMICs, and it attempts to document their accumulated experience for the guidance of those who might undertake field trials of health interventions. It can be read in its entirety as an introduction to the field and/or can serve as a reference volume during each of the different stages of planning, conducting, and analysing a field trial.

13th July 2015 • comment

Las solicitudes para fondos o apoyos difieren substancialmente dependiendo de la organización a la que se esté aplicando, ya que cada una de ellas tiene sus propios objetivos organizacionales, los cuales es importante entender cuando se está considerando a que fondo o apoyo aplicar. En este artículo ofrecemos consejos prácticos e información para escribir solicitudes para fondos o apoyos, los cuales pueden ser aplicados a solicitudes de todo tipo, desde becas hasta solicitudes para financiamientos grandes.

7th July 2015 • comment

Grant applications differ substantially depending on the individual funding organisation, and each funding organisation has its own organisational aims, which are important to understand when you are considering which grant to apply to. In this article we provide practical tips and information for writing grant applications, which can be applied to grant applications of all sorts, from fellowships to large funding applications.

7th July 2015 • comment

In celebration of Global Health Trials' fifth birthday (May 11th 2015) Professor Trudie Lang, Principal Investigator of the programme, talks to us about why Global Health Trials was started, why people should share their experience, and what the future holds.

8th May 2015 • comment

Research Administration and Grant Management

by Research Administration Tools.org

Links to resources provided by iRIM (the Initiative on Research and Innovation Management) - free online presentations and tutorials relating to how to manage grants and perform administration of clinical research projects effectively.

26th March 2015 • comment
2nd February 2015 • comment

The ISARIC-WHO Clinical Characterisation Protocol for Severe Emerging Infection, with supporting documents. Under WHO ERB review.

29th October 2014 • comment

Ten Simple Rules for Aspiring Scientists in a Low-Income Country

by Edgardo Moreno, José-María Gutiérrez
4th September 2014 • comment

A programme set up by WHO together with major publishers to provide free or very low cost online access to the major journals to local, not-for-profit institutions in developing countries.

5th June 2014 • comment
7th May 2014 • comment

This resource was used to train health professionals on how to record key data on pregnancies and deliveries for women participating in the Fetal Growth Longitudinal Study (FGLS) and Newborn Cross Sectional Study (NCSS). http://www.medscinet.net/Intergrowth/patientinfodocs/Pregnancy%20and%20Delivery%20Form%20Instructions.pdf

25th April 2014 • comment

Basic Neonatal Care Manual

by INTERGROWTH-21st

The INTERGROWTH-21st Project used this manual to standardize definitions, treatment and management recommendations of neonatal morbidities.  http://www.medscinet.net/Intergrowth/patientinfodocs/Neonatal%20Manual%20Final.pdf

25th April 2014 • comment

Anthropometry Handbook

by INTERGROWTH-21st

This handbook describes the methods used to perform accurate, precise and standardized anthropometric measurements for all components of the INTERGROWTH-21st study, including:

  • height and weight of pregnant mothers
  • birth weight, length and head circumference of newborns
  • weight, length and head circumference of preterm babies
http://www.medscinet.net/Intergrowth/patientinfodocs/Anthropometry%20Handbook%20April%202012.pdf

25th April 2014 • comment

This protocol outlines the technique for measuring symphysis fundus height. http://www.medscinet.net/Intergrowth/patientinfodocs/Measurement%20of%20Symphysis%20Fundus%20Height.pdf

25th April 2014 • comment

This protocol outlines the technique for taking a pregnant woman's blood pressure. http://www.medscinet.net/Intergrowth/patientinfodocs/BP%20protocol.pdf

25th April 2014 • comment

Ultrasound Operations Manual

by INTERGROWTH-21st

The aims of this manual are to ensure all trained ultrasonographers are familiar with the standardized way measurements should be taken for the purposes of using the INTERGROWTH-21st growth standards, including standardization of the way the equipment should be used, ultrasound findings are recorded, data is entered and transfered, and how to train, asesses and certify these standardized techniques.  http://www.medscinet.net/Intergrowth/patientinfodocs/US%20Manual%20FINAL.pdf

25th April 2014 • comment
28th March 2014 • comment
25th February 2014 • comment

ESSENCE on Health Research have created a good practice document on research costing. It includes a review of the funding practices related to the definition and funding of direct and indirect costs. 

18th December 2013 • comment
23rd July 2013 • comment

We share a brief on the MCL shared at at the Women Deliver Conference 2013.

4th June 2013 • comment

Researchers can often be tripped up by issues they encounter in developing regions and remote areas. Although no definitive answers are provided (there are just too many options and unknowns), the following issues should be considered when planning such a trial.  

10th May 2013 • comment

Despite published guidance on writing the abstract in the PRISMA Statement guiding the reporting of systematic reviews in general and elsewhere, evaluations show that reporting of systematic reviews in journal and conference abstracts is poor. Teh authors developed consensus-based reporting guidelines as an extension to the PRISMA Statement on good reporting of systematic reviews and meta-analyses in abstracts.

10th April 2013 • comment

In determining the feasibility of establishing a biorepository at your facility, there are several key factors to consider. But first, there are a few that must be in place before commencing. They are:

  • The commitment of your institutional
  • The trust of the community within which you work
  • Informed consents that allow specimens to be used for multiple research studies
  • Vision/commitment for the distribution and sharing of biospecimens and data with the wider scientific community
We attach here the facility checklist for biospecimen collection and storage, organized by topic, along with the relevant Best Practices from ISBER, for assessing the readiness your facility. The purpose of these checklists are to 1) identify any potential barriers to setting up long-term storage of biospecimens on site; and 2) enable you to take action, as needed.

8th January 2013 • comment

A sample plan for sample collection with regards to a potential novel coronavirus outbreak, developed by Kenneth Baillie and ISARIC's Working Group 3.

8th December 2012 • comment

Research reporting guidelines are standard statements that provide guidance on how to report research methodology and findings. These are in the form of checklists, flow diagrams or texts. Most of the biomedical journals require authors to comply with these guidelines. Guidelines are available for reporting various study designs:

  • CONSORT Statement (reporting of randomized controlled trials)
  • STARD (reporting of diagnostic accuracy studies)
  • STROBE (reporting of observational studies in epidemiology)
  • PRISMA (reporting of systematic reviews)
  • MOOSE (reporting of meta-analyses of observational studies)

26th October 2012 • comment

A range of downloadable templates and tools for Clinical Research, including monitoring checklists, budget spreadsheets, informed consent forms, SOPs and so on.

9th August 2012 • comment
10th July 2012 • comment
4th December 2011 • comment
4th December 2011 • comment

Five seed documents are provided here for use in clinical research, which can be adapted and altered for each study. Here we provide a template concept protocol, a study protocol, a CRF, an informed consent form, and a generic SOP.

30th November 2011 • comment

It is a recommendation of some IRB/ECs that back translation is included as a necessary step for the translation of some clinical trial documentation, including informed consent documents. This article explains the reasons for back translation, and takes you through how to effectively perform this step, including explaining how to find a suitable translator for the task.

9th June 2011 • comment

During the setting up of our trial in Cameroon we met several operational issues that we needed to overcome. For some of these issues we developed some tools and we have made them available here so that other research groups can use them in their clinical trials.

13th May 2011 • comment

An article about a workshop that assessed ethical review and informed consent in vulnerable populations. This article aims to prompt a debate leading to better guiding principles on health research in constrained settings

24th January 2011 • comment

A set of 4 consent templates for clinical trials, interview studies, observation studies and sampling only studies.

29th November 2010 • comment

This article was written by a researcher from Sri Lanka and presents a very helpful overview on Biomedical Ethics. This article will be helpful to all levels of research staff and others who might want an accessible overview

26th October 2010 • comment

The Trial Protocol Tool: a tool to help researchers to write a high quality protocol for a randomised controlled trial AVAILABLE IN SPANISH AND ENGLISH

10th August 2010 • comment

What is the definition of clinical trial monitoring? Who can be a monitor? What are the monitor's roles and responsibilities? Read on for some answers.

2nd February 2010 • comment

An overview of different types of clinical trial oversight committees, including steering committees and data safety monitoring committees.

21st November 2009 • comment

Coming soon! A paper series on clinical trial design for tropical diseases. Read more here and get involved!

21st November 2009 • comment

Who should write up the results of the clinical trial? Are there guidelines on what should be included in the paper? This article answers these questions.

21st November 2009 • comment

Ticking the last box: once the trial has ended it is important to ensure correct site closure and archiving of study files.

21st November 2009 • comment

Considerations for pharmacovigilance and safety reporting.

21st November 2009 • comment

The effort invested in pre-trial planning and preparation more than pays off in terms of smooth operations, happy staff, happy participants, good recruitment and ultimately high quality data.

21st November 2009 • comment

Clinical trials don't have to be expensive! Here are some tips for finding funding and drafting a realistic budget for your study.

21st November 2009 • comment

Good data management practices are essential to the success of a trial because they help to ensure that the data collected is complete and accurate. This article contains some tips to help you get started with data management.

21st November 2009 • comment

Clinical trial regulations can be confusing and unwieldy to researchers. The intention of this section is to explain what regulations exist, where they apply and how to work through them in a sensible and pragmatic way to determine what is applicable to any given trial.

21st November 2009 • comment